Gene
acp1
- ID
- ZDB-GENE-050327-12
- Name
- acid phosphatase 1
- Symbol
- acp1 Nomenclature History
- Previous Names
-
- im:6910498
- zgc:110844
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to enable protein tyrosine phosphatase activity. Acts upstream of or within pronephros development. Predicted to be located in cytoplasm. Is expressed in gut and liver. Human ortholog(s) of this gene implicated in several diseases, including attention deficit hyperactivity disorder; conduct disorder; diabetes mellitus (multiple); diabetic retinopathy; and obesity. Orthologous to human ACP1 (acid phosphatase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6910498 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Li et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR023485 | Phosphotyrosine protein phosphatase I |
| Family | IPR002115 | Protein-tyrosine phosphatase, low molecular weight, mammalian |
| Family | IPR017867 | Protein-tyrosine phosphatase, low molecular weight |
| Family | IPR050438 | Low Molecular Weight Phosphotyrosine Protein Phosphatase |
| Homologous_superfamily | IPR036196 | Phosphotyrosine protein phosphatase I superfamily |
Domain Details Per Protein
| Protein | Length | Low Molecular Weight Phosphotyrosine Protein Phosphatase | Phosphotyrosine protein phosphatase I | Phosphotyrosine protein phosphatase I superfamily | Protein-tyrosine phosphatase, low molecular weight | Protein-tyrosine phosphatase, low molecular weight, mammalian |
|---|---|---|---|---|---|---|
|
UniProtKB:F1QH99
|
158 | |||||
|
UniProtKB:A0A8M1P258
|
158 |
Interactions and Pathways
No data available
Plasmids
No data available