Gene
adcyap1r1a
- ID
- ZDB-GENE-050315-1
- Name
- adenylate cyclase activating polypeptide 1a (pituitary) receptor type I
- Symbol
- adcyap1r1a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to have G protein-coupled peptide receptor activity and peptide hormone binding activity. Involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway and phospholipase C-activating G protein-coupled receptor signaling pathway. Predicted to localize to integral component of membrane. Is expressed in several structures, including central nervous system; eye; gut; heart; and pleuroperitoneal region. Orthologous to human ADCYAP1R1 (ADCYAP receptor type I).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| post-traumatic stress disorder | adcyap1r1awz18/wz18 | standard conditions | Biran et al., 2020 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017983 | GPCR, family 2, secretin-like, conserved site |
| Domain | IPR001879 | GPCR, family 2, extracellular hormone receptor domain |
| Domain | IPR017981 | GPCR, family 2-like, 7TM |
| Family | IPR000832 | GPCR, family 2, secretin-like |
| Family | IPR002285 | GPCR, family 2, pituitary adenylate cyclase activating polypeptide type 1 receptor |
| Family | IPR050332 | G-protein coupled receptor 2 |
| Homologous_superfamily | IPR036445 | GPCR family 2, extracellular hormone receptor domain superfamily |
Domain Details Per Protein
| Protein | Length | GPCR, family 2, extracellular hormone receptor domain | GPCR family 2, extracellular hormone receptor domain superfamily | GPCR, family 2-like, 7TM | GPCR, family 2, pituitary adenylate cyclase activating polypeptide type 1 receptor | GPCR, family 2, secretin-like | GPCR, family 2, secretin-like, conserved site | G-protein coupled receptor 2 |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q5C8U8
|
478 | |||||||
|
UniProtKB:E7FF76
|
445 | |||||||
|
UniProtKB:Q5C8U6
|
479 | |||||||
|
UniProtKB:Q5C8V0
|
451 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| aberrant processed transcript |
adcyap1r1a-202
(1)
|
Ensembl | 1,209 nt | ||
| mRNA |
adcyap1r1a-201
(1)
|
Ensembl | 1,102 nt | ||
| mRNA |
adcyap1r1a-203
(1)
|
Ensembl | 9,167 nt | ||
| mRNA |
adcyap1r1a-204
(1)
|
Ensembl | 1,186 nt |
Interactions and Pathways
No data available
Plasmids
No data available