Gene
btc
- ID
- ZDB-GENE-050311-1
- Name
- betacellulin, epidermal growth factor family member
- Symbol
- btc Nomenclature History
- Previous Names
-
- zgc:153253
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable epidermal growth factor receptor binding activity and growth factor activity. Predicted to be involved in epidermal growth factor receptor signaling pathway; positive regulation of cell population proliferation; and positive regulation of mitotic nuclear division. Predicted to be located in membrane. Predicted to be active in extracellular space. Is expressed in heart and retina. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus and type 2 diabetes mellitus. Orthologous to human BTC (betacellulin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000742 | EGF-like domain |
Domain Details Per Protein
| Protein | Length | EGF-like domain |
|---|---|---|
|
UniProtKB:A0A0R4INZ6
|
178 | |
|
UniProtKB:Q1LVQ0
|
178 |
Interactions and Pathways
No data available
Plasmids
No data available