Gene

ndufb11

ID

ZDB-GENE-050309-25

Name

NADH:ubiquinone oxidoreductase subunit B11

Symbol

ndufb11 Nomenclature History

Previous Names

im:6897973 (1)
si:dkey-6n6.4 (1)

Type

protein_coding_gene

Location

Chr: 8 Mapping Details/Browsers

Description

Acts upstream of or within heart development and vasculature development. Predicted to be located in membrane and mitochondrion. Predicted to be part of mitochondrial respiratory chain complex I. Is expressed in several structures, including alar plate midbrain region; digestive system; intestinal bulb primordium; optic tectum; and pectoral fin. Human ortholog(s) of this gene implicated in linear skin defects with multiple congenital anomalies 3 and nuclear type mitochondrial complex I deficiency 30. Orthologous to human NDUFB11 (NADH:ubiquinone oxidoreductase subunit B11).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6897973 (8 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from Shehata et al., 2015
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ndufb11 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
linear skin defects with multiple congenital anomalies 3	Alliance	Linear skin defects with multiple congenital anomalies 3	300952
nuclear type mitochondrial complex I deficiency 30	Alliance	?Mitochondrial complex I deficiency, nuclear type 30	301021

Associated With ndufb11 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR019329	NADH:ubiquinone oxidoreductase, ESSS subunit

Domain Details Per Protein

Protein	Length	NADH:ubiquinone oxidoreductase, ESSS subunit
UniProtKB:Q1LYN0 InterPro	150

Transcripts

Genome Browsers

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	ndufb11-201 (1) Ensembl	Ensembl		816 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations