Gene
g6pc1a.2
- ID
- ZDB-GENE-050309-17
- Name
- glucose-6-phosphatase catalytic subunit 1a, tandem duplicate 2
- Symbol
- g6pc1a.2 Nomenclature History
- Previous Names
-
- g6pca.2
- im:6895556
- im:7148077
- si:ch211-215l11.5
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have glucose-6-phosphatase activity. Involved in response to (R)-carnitine. Predicted to localize to endoplasmic reticulum; endoplasmic reticulum membrane; and integral component of membrane. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and type 2 diabetes mellitus. Is expressed in liver; male organism; and yolk syncytial layer. Orthologous to human G6PC (glucose-6-phosphatase catalytic subunit).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 20 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6895556 (12 images)
- IMAGE:7148077 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| glycogen storage disease Ia | Alliance | Glycogen storage disease Ia | 232200 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Glucose-6-phosphatase | Phosphatidic acid phosphatase type 2/haloperoxidase | Phosphatidic acid phosphatase type 2/haloperoxidase superfamily |
|---|---|---|---|---|
|
UniProtKB:F1QHF8
|
355 | |||
|
UniProtKB:A2VD27
|
351 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
g6pca.2-201
(1)
|
Ensembl | 2,318 nt | ||
| ncRNA |
g6pca.2-002
(1)
|
Ensembl | 2,422 nt | ||
| ncRNA |
g6pca.2-003
(1)
|
Ensembl | 758 nt | ||
| ncRNA |
g6pca.2-004
(1)
|
Ensembl | 720 nt |
Interactions and Pathways
No data available
Plasmids
No data available