Gene

agtr2

ID
ZDB-GENE-050306-56
Name
angiotensin II receptor, type 2
Symbol
agtr2 Nomenclature History
Previous Names
  • zgc:113016
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have angiotensin type II receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway; inflammatory response; and positive regulation of blood vessel diameter. Predicted to localize to plasma membrane. Human ortholog(s) of this gene implicated in IgA glomerulonephritis; end stage renal failure; hypoglycemia; intellectual disability; and vesicoureteral reflux. Is expressed in several structures, including blood vasculature; post-vent region; posterior lateral plate mesoderm; trunk; and vascular cord. Orthologous to human AGTR2 (angiotensin II receptor type 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With agtr2 Human Ortholog
No data available
Associated With agtr2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR017452 GPCR, rhodopsin-like, 7TM
Family IPR000248 Angiotensin II receptor family
Family IPR000276 G protein-coupled receptor, rhodopsin-like
Domain Details Per Protein
Protein Length Angiotensin II receptor family GPCR, rhodopsin-like, 7TM G protein-coupled receptor, rhodopsin-like
UniProtKB:Q5CZS2 360
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA agtr2-201 (1) Ensembl 1,875 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations