Gene

plxnb1a

ID

ZDB-GENE-050302-63

Name

plexin b1a

Symbol

plxnb1a Nomenclature History

Previous Names

im:7054247 (1)
si:ch211-220i18.5
wu:fb83a09

Type

protein_coding_gene

Location

Chr: 23 Mapping Details/Browsers

Description

Predicted to enable semaphorin receptor activity. Acts upstream of or within axon extension. Predicted to be located in membrane. Predicted to be part of semaphorin receptor complex. Predicted to be active in plasma membrane. Orthologous to human PLXNB1 (plexin B1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Knickmeyer et al., 2021

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Hilario et al., 2009
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With plxnb1a Human Ortholog

No data available

Associated With plxnb1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001627	Sema domain
Domain	IPR002909	IPT domain
Domain	IPR013548	Plexin, cytoplasmic RasGAP domain
Domain	IPR016201	PSI domain
Domain	IPR041019	Plexin, TIG domain 1
Domain	IPR041362	Plexin, TIG domain 2
Domain	IPR046800	Plexin, cytoplasmic RhoGTPase-binding domain
Family	IPR031148	Plexin family
Homologous_superfamily	IPR008936	Rho GTPase activation protein
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR014756	Immunoglobulin E-set
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR036352	Sema domain superfamily
Repeat	IPR002165	Plexin repeat

Domain Details Per Protein

Protein	Length	Immunoglobulin E-set	Immunoglobulin-like fold	IPT domain	Plexin, cytoplasmic RasGAP domain	Plexin, cytoplasmic RhoGTPase-binding domain	Plexin family	Plexin repeat	Plexin, TIG domain 1	Plexin, TIG domain 2	PSI domain	Rho GTPase activation protein	Sema domain	Sema domain superfamily	WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:A0A8M3B5Y3 InterPro	1930
UniProtKB:A0A8M3AMN7 InterPro	2138
UniProtKB:A0A8M1QKJ0 InterPro	2133

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	plxnb1a-201 (1) Ensembl	Ensembl	779 nt	Select Tool ZFIN BLAST
mRNA	plxnb1a-202 (1) Ensembl	Ensembl	914 nt	Select Tool ZFIN BLAST
mRNA	plxnb1a-203 (1) Ensembl	Ensembl	3,945 nt	Select Tool ZFIN BLAST
mRNA	plxnb1a-204 (1) Ensembl	Ensembl	508 nt	Select Tool ZFIN BLAST
mRNA	plxnb1a-205 (1) Ensembl	Ensembl	5,838 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations