Gene
aox6
- ID
- ZDB-GENE-050208-742
- Name
- aldehyde oxidase 6
- Symbol
- aox6 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to enable aldehyde oxidase activity. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis. Orthologous to human AOX1 (aldehyde oxidase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR006058 | 2Fe-2S ferredoxin, iron-sulphur binding site |
| Domain | IPR000674 | Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead |
| Domain | IPR001041 | 2Fe-2S ferredoxin-type iron-sulfur binding domain |
| Domain | IPR002346 | Molybdopterin dehydrogenase, FAD-binding |
| Domain | IPR002888 | [2Fe-2S]-binding |
| Domain | IPR005107 | CO dehydrogenase flavoprotein, C-terminal |
| Domain | IPR008274 | Aldehyde oxidase/xanthine dehydrogenase, first molybdopterin binding domain |
| Domain | IPR016166 | FAD-binding domain, PCMH-type |
| Domain | IPR046867 | Aldehyde oxidase/xanthine dehydrogenase, second molybdopterin binding domain |
| Family | IPR016208 | Aldehyde oxidase/xanthine dehydrogenase-like |
| Homologous_superfamily | IPR012675 | Beta-grasp domain superfamily |
| Homologous_superfamily | IPR016167 | FAD-binding, type PCMH, subdomain 1 |
| Homologous_superfamily | IPR016169 | FAD-binding, type PCMH, subdomain 2 |
| Homologous_superfamily | IPR036010 | 2Fe-2S ferredoxin-like superfamily |
| Homologous_superfamily | IPR036318 | FAD-binding, type PCMH-like superfamily |
| Homologous_superfamily | IPR036683 | CO dehydrogenase flavoprotein, C-terminal domain superfamily |
| Homologous_superfamily | IPR036856 | Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily |
| Homologous_superfamily | IPR036884 | [2Fe-2S]-binding domain superfamily |
| Homologous_superfamily | IPR037165 | Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily |
Domain Details Per Protein
| Protein | Length | [2Fe-2S]-binding | [2Fe-2S]-binding domain superfamily | 2Fe-2S ferredoxin, iron-sulphur binding site | 2Fe-2S ferredoxin-like superfamily | 2Fe-2S ferredoxin-type iron-sulfur binding domain | Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead | Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily | Aldehyde oxidase/xanthine dehydrogenase, first molybdopterin binding domain | Aldehyde oxidase/xanthine dehydrogenase-like | Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily | Aldehyde oxidase/xanthine dehydrogenase, second molybdopterin binding domain | Beta-grasp domain superfamily | CO dehydrogenase flavoprotein, C-terminal | CO dehydrogenase flavoprotein, C-terminal domain superfamily | FAD-binding domain, PCMH-type | FAD-binding, type PCMH-like superfamily | FAD-binding, type PCMH, subdomain 1 | FAD-binding, type PCMH, subdomain 2 | Molybdopterin dehydrogenase, FAD-binding |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F1Q5R8
|
1338 |
Interactions and Pathways
No data available
Plasmids
No data available