Gene

cfhl3

ID

ZDB-GENE-050208-423

Name

complement factor H like 3

Symbol

cfhl3 Nomenclature History

Previous Names

si:ch211-207o17.4

Type

protein_coding_gene

Location

Chr: 22 Mapping Details/Browsers

Description

Human ortholog(s) of this gene implicated in acute myeloid leukemia; age related macular degeneration 1; atypical hemolytic-uremic syndrome; and multiple myeloma. Is expressed in several structures, including digestive system; eye; fin; gill; and heart. Orthologous to several human genes including F13B (coagulation factor XIII B chain); CFHR1 (complement factor H related 1); and CFHR4 (complement factor H related 4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Sun et al., 2010

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cfhl3 Human Ortholog

No data available

Associated With cfhl3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000436	Sushi/SCR/CCP domain
Family	IPR051503	Complement System Regulators and Virion Entry Mediators
Homologous_superfamily	IPR035976	Sushi/SCR/CCP superfamily

Domain Details Per Protein

Protein	Length	Complement System Regulators and Virion Entry Mediators	Sushi/SCR/CCP domain	Sushi/SCR/CCP superfamily
UniProtKB:A0A8M9PDT0 InterPro	454
UniProtKB:A0A0R4IIN5 InterPro	632
UniProtKB:E2FHP7 InterPro	630

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	cfhl3-202 (1) Ensembl	Ensembl	956 nt	Select Tool
mRNA	cfhl3-203 (1) Ensembl	Ensembl	884 nt	Select Tool
mRNA	cfhl3-205 (1) Ensembl	Ensembl	2,220 nt	Select Tool
mRNA	cfhl3-206 (1) Ensembl	Ensembl	2,916 nt	Select Tool ZFIN BLAST
ncRNA	cfhl3-002 (1) Ensembl	Ensembl	605 nt	Select Tool
ncRNA	cfhl3-004 (1) Ensembl	Ensembl	906 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations