Gene
cnnm2a
- ID
- ZDB-GENE-050208-36
- Name
- cyclin and CBS domain divalent metal cation transport mediator 2a
- Symbol
- cnnm2a Nomenclature History
- Previous Names
-
- im:7136247
- si:ch211-67n3.4
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to have magnesium ion transmembrane transporter activity. Involved in brain development and magnesium ion homeostasis. Predicted to localize to plasma membrane. Human ortholog(s) of this gene implicated in renal hypomagnesemia 6. Is expressed in several structures, including brain; digestive system; midbrain hindbrain boundary neural keel; pleuroperitoneal region; and scale. Orthologous to human CNNM2 (cyclin and CBS domain divalent metal cation transport mediator 2).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 12 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7136247 (2 images)
Wild Type Expression Summary
- All Phenotype Data
- 12 figures from 3 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
renal hypomagnesemia 6 | Alliance | Hypomagnesemia 6, renal | 613882 |
Hypomagnesemia, seizures, and impaired intellectual development 1 | 616418 |
Human Disease | Fish | Conditions | Citations |
---|---|---|---|
schizophrenia | cnnm2aa357/a357 | standard conditions | Thyme et al., 2019 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Ancient conserved domain protein family | CBS domain | CBS domain superfamily | CNNM, transmembrane domain | Ion transporter-like, CBS domain |
---|---|---|---|---|---|---|
UniProtKB:A2ATX7
|
811 |
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
cnnm2a-201
(1)
|
Ensembl | 2,817 nt |
Interactions and Pathways
No data available
Plasmids
No data available