Gene
slx4
- ID
- ZDB-GENE-050208-359
- Name
- SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
- Symbol
- slx4 Nomenclature History
- Previous Names
-
- btbd12
- fancp (1)
- si:dkey-44g23.4
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to contribute to 3'-flap endonuclease activity; 5'-flap endonuclease activity; and crossover junction endodeoxyribonuclease activity. Involved in gall bladder development and hepatic duct development. Predicted to localize to Slx1-Slx4 complex. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group P. Orthologous to human SLX4 (SLX4 structure-specific endonuclease subunit).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Fanconi anemia complementation group P | Alliance | Fanconi anemia, complementation group P | 613951 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | BTB/POZ domain | SKP1/BTB/POZ domain superfamily | Structure-specific endonuclease subunit Slx4 | Zinc finger C2H2-type |
|---|---|---|---|---|---|
|
UniProtKB:F1QPU2
|
1719 | ||||
|
UniProtKB:A0A8M1RN23
|
1720 |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance