Gene
ambra1b
- ID
- ZDB-GENE-050208-235
- Name
- autophagy/beclin-1 regulator 1b
- Symbol
- ambra1b Nomenclature History
- Previous Names
-
- im:7146310
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Involved in chordate embryonic development; locomotory behavior; and skeletal muscle fiber development. Predicted to localize to intracellular membrane-bounded organelle. Is expressed in several structures, including blastodisc; oral cavity; otic vesicle; pleuroperitoneal region; and tail bud. Orthologous to human AMBRA1 (autophagy and beclin 1 regulator 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7146310 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 24 figures from 5 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019775 | WD40 repeat, conserved site |
| Family | IPR052596 | Activating Molecule in BECN1-Regulated Autophagy |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
| Repeat | IPR001680 | WD40 repeat |
Domain Details Per Protein
| Protein | Length | Activating Molecule in BECN1-Regulated Autophagy | WD40 repeat | WD40 repeat, conserved site | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:X1WHY6
|
1360 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ambra1b-201
(1)
|
Ensembl | 9,233 nt | ||
| mRNA |
ambra1b-202
(1)
|
Ensembl | 8,596 nt |
Interactions and Pathways
No data available
Plasmids
No data available