Gene
fgf23
- ID
- ZDB-GENE-050201-4
- Name
- fibroblast growth factor 23
- Symbol
- fgf23 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to enable growth factor activity and type 1 fibroblast growth factor receptor binding activity. Acts upstream of or within calcium ion homeostasis. Predicted to be active in cytoplasm and extracellular space. Is expressed in corpuscles of Stannius; gill; and kidney. Human ortholog(s) of this gene implicated in autosomal dominant hypophosphatemic rickets. Orthologous to human FGF23 (fibroblast growth factor 23).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from 9 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant hypophosphatemic rickets | Alliance | Hypophosphatemic rickets, autosomal dominant | 193100 |
| Tumoral calcinosis, hyperphosphatemic, familial, 2 | 617993 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cytokine IL1/FGF | Fibroblast growth factor family |
|---|---|---|---|
|
UniProtKB:Q5MK87
|
258 |
Interactions and Pathways
No data available
Plasmids
No data available