Gene
mag
- ID
- ZDB-GENE-041217-24
- Name
- myelin associated glycoprotein
- Symbol
- mag Nomenclature History
- Previous Names
-
- siglec-4 (1)
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Exhibits carbohydrate binding activity and identical protein binding activity. Predicted to be involved in cell adhesion. Predicted to localize to plasma membrane. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 75. Is expressed in nervous system. Orthologous to human MAG (myelin associated glycoprotein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 17 figures from 10 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cssl:d821 (17 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Djannatian et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hereditary spastic paraplegia 75 | Alliance | Spastic paraplegia 75, autosomal recessive | 616680 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003598 | Immunoglobulin subtype 2 |
| Domain | IPR003599 | Immunoglobulin domain subtype |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Domain | IPR013098 | Immunoglobulin I-set |
| Domain | IPR013106 | Immunoglobulin V-set domain |
| Family | IPR051036 | Sialic acid-binding Ig-like lectin |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Immunoglobulin domain subtype | Immunoglobulin I-set | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin subtype 2 | Immunoglobulin V-set domain | Sialic acid-binding Ig-like lectin |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A0R4IQ16
|
635 | ||||||||
|
UniProtKB:A0A8M9QPU2
|
567 | ||||||||
|
UniProtKB:F1QSA4
|
653 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
mag-201
(1)
|
Ensembl | 539 nt | ||
| mRNA |
mag-202
(1)
|
Ensembl | 2,180 nt | ||
| mRNA |
mag-203
(1)
|
Ensembl | 2,496 nt | ||
| mRNA |
mag-204
(1)
|
Ensembl | 2,126 nt | ||
| mRNA |
mag-205
(1)
|
Ensembl | 2,212 nt | ||
| mRNA |
mag-206
(1)
|
Ensembl | 2,248 nt | ||
| mRNA |
mag-207
(1)
|
Ensembl | 2,351 nt | ||
| mRNA |
mag-208
(1)
|
Ensembl | 2,297 nt |
Interactions and Pathways
No data available
Plasmids
No data available