Gene
ift27
- ID
- ZDB-GENE-041212-9
- Name
- intraflagellar transport 27 homolog (Chlamydomonas)
- Symbol
- ift27 Nomenclature History
- Previous Names
-
- rabl4
- zgc:101893
- Type
- protein_coding_gene
- Location
- Unmapped
- Description
- Predicted to have GTPase activity. Involved in cilium assembly; kidney development; and regulation of melanosome transport. Predicted to localize to endomembrane system. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome 19. Orthologous to human IFT27 (intraflagellar transport 27).
- Genome Resources
-
- Alliance (1)
- Gene:494045 (1)
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7148811 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Bardet-Biedl syndrome 19 | Alliance | Bardet-Biedl syndrome 19 | 615996 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Intraflagellar transport protein 27 homologue, eukaryotes | P-loop containing nucleoside triphosphate hydrolase | Small GTPase | Small GTP-binding domain |
|---|---|---|---|---|---|
|
UniProtKB:Q5PR92
|
186 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance