Gene

ptgr1.1

ID

ZDB-GENE-041212-80

Name

prostaglandin reductase 1, tandem duplicate 1

Symbol

ptgr1.1 Nomenclature History

Previous Names

ptgr1
ltb4dh (1)
wu:fj35e05
zgc:101689

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to have 15-oxoprostaglandin 13-oxidase activity and 2-alkenal reductase [NAD(P)+] activity. Predicted to be involved in oxidation-reduction process. Predicted to localize to cytoplasm. Is expressed in digestive system; nervous system; and pectoral fin. Orthologous to human PTGR1 (prostaglandin reductase 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6905119 (10 images)
IMAGE:7165235 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ptgr1.1 Human Ortholog

No data available

Associated With ptgr1.1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR013149	Alcohol dehydrogenase-like, C-terminal
Domain	IPR020843	Polyketide synthase, enoylreductase domain
Domain	IPR041694	Oxidoreductase, N-terminal domain
Family	IPR014190	Leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase
Family	IPR045010	Medium-chain dehydrogenase/reductase
Homologous_superfamily	IPR011032	GroES-like superfamily
Homologous_superfamily	IPR036291	NAD(P)-binding domain superfamily

Domain Details Per Protein

Protein	Length	Alcohol dehydrogenase-like, C-terminal	GroES-like superfamily	Leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase	Medium-chain dehydrogenase/reductase	NAD(P)-binding domain superfamily	Oxidoreductase, N-terminal domain	Polyketide synthase, enoylreductase domain
UniProtKB:Q5PRB9 InterPro	329

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	ptgr1-201 (1) Ensembl	Ensembl	2,249 nt	Select Tool
ncRNA	ptgr1-002 (1) Ensembl	Ensembl	772 nt	Select Tool
ncRNA	ptgr1-003 (1) Ensembl	Ensembl	790 nt	Select Tool
ncRNA	ptgr1-004 (1) Ensembl	Ensembl	841 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations