Gene

lxn

ID

ZDB-GENE-041212-18

Name

latexin

Symbol

lxn Nomenclature History

Previous Names

RARRES1 (1)
wu:fk66c02
zgc:103612

Type

protein_coding_gene

Location

Chr: 15 Mapping Details/Browsers

Description

Predicted to enable metalloendopeptidase inhibitor activity. Predicted to act upstream of or within negative regulation of peptidase activity. Predicted to be active in extracellular space. Is expressed in annular ligament and corneal endothelium. Orthologous to several human genes including LXN (latexin).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:103612 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Maimouni et al., 2019
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With lxn Human Ortholog

No data available

Associated With lxn Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR049897	Latexin-type cystatin domain
Family	IPR009684	Latexin
Homologous_superfamily	IPR046350	Cystatin superfamily

Domain Details Per Protein

Protein	Length	Cystatin superfamily	Latexin	Latexin-type cystatin domain
UniProtKB:A0A8M9Q0C1 InterPro	269
UniProtKB:A0A8M2BGX5 InterPro	232
UniProtKB:A0A8M3ASB5 InterPro	243
UniProtKB:Q5PR40 InterPro	271
UniProtKB:A0A286Y993 InterPro	270