Gene

anapc4

ID

ZDB-GENE-041212-10

Name

anaphase promoting complex subunit 4

Symbol

anapc4 Nomenclature History

Previous Names

si:dkey-90m5.2
zgc:101872

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Description

Predicted to contribute to ubiquitin protein ligase activity. Predicted to be involved in anaphase-promoting complex-dependent catabolic process; positive regulation of mitotic metaphase/anaphase transition; and protein K11-linked ubiquitination. Predicted to localize to anaphase-promoting complex and nuclear periphery. Orthologous to human ANAPC4 (anaphase promoting complex subunit 4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With anapc4 Human Ortholog

No data available

Associated With anapc4 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR024790	Anaphase-promoting complex subunit 4, long domain
Domain	IPR024977	Anaphase-promoting complex subunit 4-like, WD40 domain
Family	IPR017169	Anaphase-promoting complex subunit 4, metazoa
Family	IPR024789	Anaphase-promoting complex subunit 4
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily

Domain Details Per Protein

Protein	Length	Anaphase-promoting complex subunit 4	Anaphase-promoting complex subunit 4-like, WD40 domain	Anaphase-promoting complex subunit 4, long domain	Anaphase-promoting complex subunit 4, metazoa	WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:A0A8M3AW62 InterPro	804
UniProtKB:A0A8M2B7D6 InterPro	806
UniProtKB:Q5PR93 InterPro	797

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	anapc4-201 (1) Ensembl	Ensembl	2,726 nt	Select Tool ZFIN BLAST
mRNA	anapc4-202 (1) Ensembl	Ensembl	915 nt	Select Tool ZFIN BLAST
ncRNA	anapc4-003 (1) Ensembl	Ensembl	784 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations