Gene
flvcr2b
- ID
- ZDB-GENE-041210-312
- Name
- FLVCR choline and putative heme transporter 2b
- Symbol
- flvcr2b Nomenclature History
- Previous Names
-
- flvsr2a
- fc07b07
- si:ch211-119b12.6
- wu:fc07b07
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have heme binding activity and heme transporter activity. Predicted to be involved in heme export. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome. Orthologous to human FLVCR2 (FLVCR heme transporter 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome | Alliance | Proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome | 225790 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Major facilitator superfamily | Major facilitator superfamily domain | MFS transporter superfamily |
|---|---|---|---|---|
|
UniProtKB:E9QH04
|
495 | |||
|
UniProtKB:A0A8M9Q757
|
495 | |||
|
UniProtKB:A0A8M2B829
|
485 | |||
|
UniProtKB:A0A8M9Q308
|
485 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
flvcr2b-201
(1)
|
Ensembl | 2,505 nt | ||
| mRNA |
flvcr2b-202
(1)
|
Ensembl | 1,458 nt |
Interactions and Pathways
No data available
Plasmids
No data available