Gene

tnnt2e

ID

ZDB-GENE-041210-27

Name

troponin T2e, cardiac

Symbol

tnnt2e Nomenclature History

Previous Names

si:ch211-136g2.1

Type

protein_coding_gene

Location

Chr: 4 Mapping Details/Browsers

Description

Predicted to contribute to calcium-dependent ATPase activity and tropomyosin binding activity. Predicted to be involved in cardiac muscle contraction; sarcomere organization; and skeletal muscle contraction. Predicted to localize to troponin complex. Human ortholog(s) of this gene implicated in intrinsic cardiomyopathy (multiple). Orthologous to human TNNT2 (troponin T2, cardiac type).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from In Ka et al., 2021

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tnnt2e Human Ortholog

No data available

Associated With tnnt2e Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR001978	Troponin
Family	IPR027707	Troponin T
Homologous_superfamily	IPR038077	Troponin domain superfamily

Domain Details Per Protein

Protein	Length	Troponin	Troponin domain superfamily	Troponin T
UniProtKB:A0A8M9QB81 InterPro	286
UniProtKB:Q5RIF4 InterPro	239
UniProtKB:A0A8M9QB78 InterPro	326
UniProtKB:A0A0R4IYQ0 InterPro	278
UniProtKB:A8WGB3 InterPro	249
UniProtKB:A0A8M9PUF9 InterPro	310
UniProtKB:A0A8M9PH92 InterPro	312
UniProtKB:A0A8M9Q5W5 InterPro	317
UniProtKB:A0A8M9Q5W9 InterPro	280
UniProtKB:A0A8M9Q0H5 InterPro	301
UniProtKB:Q5RIF5 InterPro	285

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	tnnt2e-201 (1) Ensembl	Ensembl	750 nt	Select Tool ZFIN BLAST
mRNA	tnnt2e-202 (1) Ensembl	Ensembl	1,549 nt	Select Tool ZFIN BLAST
mRNA	tnnt2e-203 (1) Ensembl	Ensembl	722 nt	Select Tool ZFIN BLAST
mRNA	tnnt2e-204 (1) Ensembl	Ensembl	834 nt	Select Tool ZFIN BLAST
mRNA	tnnt2e-205 (1) Ensembl	Ensembl	1,420 nt	Select Tool ZFIN BLAST
mRNA	tnnt2e-206 (1) Ensembl	Ensembl	1,346 nt	Select Tool ZFIN BLAST
mRNA	tnnt2e-207 (1) Ensembl	Ensembl	855 nt	Select Tool ZFIN BLAST
mRNA	tnnt2e-208 (1) Ensembl	Ensembl	888 nt	Select Tool ZFIN BLAST
mRNA	tnnt2e-209 (1) Ensembl	Ensembl	936 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations