Gene
aicda
- ID
- ZDB-GENE-041122-2
- Name
- activation-induced cytidine deaminase
- Symbol
- aicda Nomenclature History
- Previous Names
-
- aid (1)
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Exhibits cytidine deaminase activity. Involved in somatic cell DNA recombination. Predicted to localize to cytoplasm and nucleus. Human ortholog(s) of this gene implicated in hyperimmunoglobulin syndrome and immunodeficiency with hyper-IgM type 2. Is expressed in head and intestine. Orthologous to human AICDA (activation induced cytidine deaminase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from Rai et al., 2010
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| immunodeficiency with hyper-IgM type 2 | Alliance | Immunodeficiency with hyper-IgM, type 2 | 605258 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | APOBEC/CMP deaminase, zinc-binding | APOBEC Cytidine Deaminase | APOBEC-like, N-terminal | Cytidine and deoxycytidylate deaminase domain | Cytidine deaminase-like |
|---|---|---|---|---|---|---|
|
UniProtKB:Q5YF88
|
210 |
Interactions and Pathways
No data available
Plasmids
No data available