Gene

pcdh2aa15

ID

ZDB-GENE-041118-15

Name

protocadherin 2 alpha a 15

Symbol

pcdh2aa15 Nomenclature History

Previous Names

DrPcdh2a22 (1)
pcdh2a22 (1)
pcdh2aa15-vCP

Type

protein_coding_gene

Location

Chr: 14 Mapping Details/Browsers

Description

Predicted to enable calcium ion binding activity. Predicted to be involved in cell adhesion. Predicted to act upstream of or within homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to several human genes including PCDHA10 (protocadherin alpha 10); PCDHA12 (protocadherin alpha 12); and PCDHA13 (protocadherin alpha 13).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Tada et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pcdh2aa15 Human Ortholog

No data available

Associated With pcdh2aa15 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR020894	Cadherin conserved site
Domain	IPR002126	Cadherin-like
Domain	IPR013164	Cadherin, N-terminal
Domain	IPR031904	Cadherin, C-terminal catenin-binding domain
Domain	IPR032455	Cadherin, cytoplasmic C-terminal domain
Family	IPR050174	Protocadherin/Cadherin-related Cell Adhesion
Homologous_superfamily	IPR015919	Cadherin-like superfamily

Domain Details Per Protein

Protein	Length	Cadherin conserved site	Cadherin, C-terminal catenin-binding domain	Cadherin, cytoplasmic C-terminal domain	Cadherin-like	Cadherin-like superfamily	Cadherin, N-terminal	Protocadherin/Cadherin-related Cell Adhesion
UniProtKB:Q60H65 InterPro	939

Transcripts

Genome Browsers

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	pcdh2aa15-201 (1) Ensembl	Ensembl		3,367 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations