Gene
dph5
- ID
- ZDB-GENE-041114-85
- Name
- diphthamide biosynthesis 5
- Symbol
- dph5 Nomenclature History
- Previous Names
-
- zgc:101823
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to have diphthine synthase activity. Predicted to be involved in peptidyl-diphthamide biosynthetic process from peptidyl-histidine. Orthologous to human DPH5 (diphthamide biosynthesis 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:101823 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| neurodevelopmental disorder with short stature, prominent forehead, and feeding difficulties | Alliance | Neurodevelopmental disorder with short stature, prominent forehead, and feeding difficulties | 620070 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000878 | Tetrapyrrole methylase |
| Family | IPR004551 | Diphthine synthase |
| Homologous_superfamily | IPR014776 | Tetrapyrrole methylase, subdomain 2 |
| Homologous_superfamily | IPR014777 | Tetrapyrrole methylase, subdomain 1 |
| Homologous_superfamily | IPR035996 | Tetrapyrrole methylase superfamily |
Domain Details Per Protein
| Protein | Length | Diphthine synthase | Tetrapyrrole methylase | Tetrapyrrole methylase, subdomain 1 | Tetrapyrrole methylase, subdomain 2 | Tetrapyrrole methylase superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A0R4IU56
|
288 |
Interactions and Pathways
No data available
Plasmids
No data available