Gene
ppm1db
- ID
- ZDB-GENE-041114-27
- Name
- protein phosphatase, Mg2+/Mn2+ dependent, 1Db
- Symbol
- ppm1db Nomenclature History
- Previous Names
-
- zgc:103518 (1)
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have magnesium-dependent protein serine/threonine phosphatase activity and mitogen-activated protein kinase binding activity. Predicted to be involved in protein dephosphorylation. Human ortholog(s) of this gene implicated in breast cancer. Orthologous to human PPM1D (protein phosphatase, Mg2+/Mn2+ dependent 1D).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:103518 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| breast cancer | Alliance | Breast cancer, somatic | 114480 |
| Jansen-de Vries syndrome | 617450 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | PPM-type phosphatase, divalent cation binding | PPM-type phosphatase-like domain | PPM-type phosphatase-like domain superfamily | Protein phosphatase 2C |
|---|---|---|---|---|---|
|
UniProtKB:Q5U3H7
|
534 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ppm1db-201
(1)
|
Ensembl | 1,894 nt |
Interactions and Pathways
No data available
Plasmids
No data available