Gene
gnal
- ID
- ZDB-GENE-041114-26
- Name
- guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
- Symbol
- gnal Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to have G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Predicted to be involved in adenylate cyclase-activating dopamine receptor signaling pathway and sensory perception of chemical stimulus. Predicted to localize to heterotrimeric G-protein complex. Human ortholog(s) of this gene implicated in dystonia 25. Is expressed in brain; gill; head; and peripheral olfactory organ. Orthologous to human GNAL (G protein subunit alpha L).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| dystonia 25 | Alliance | Dystonia 25 | 615073 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR000367 | G-protein alpha subunit, group S |
| Family | IPR001019 | Guanine nucleotide binding protein (G-protein), alpha subunit |
| Homologous_superfamily | IPR011025 | G protein alpha subunit, helical insertion |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
| Protein | Length | G-protein alpha subunit, group S | G protein alpha subunit, helical insertion | Guanine nucleotide binding protein (G-protein), alpha subunit | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|
|
UniProtKB:Q5U3H6
|
379 |
Interactions and Pathways
No data available
Plasmids
No data available