Gene

ptp4a2b

ID

ZDB-GENE-041114-111

Name

protein tyrosine phosphatase 4A2b

Symbol

ptp4a2b Nomenclature History

Previous Names

PRL-2 (1)
ptp4a2
fc05f09
wu:fc05f09
wu:fi84b06
zgc:101724

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Description

Predicted to enable protein tyrosine phosphatase activity. Predicted to act upstream of or within protein dephosphorylation. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including fin; gut; head; myotome; and neuromast. Orthologous to human PTP4A2 (protein tyrosine phosphatase 4A2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ptp4a2b Human Ortholog

No data available

Associated With ptp4a2b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000387	Tyrosine-specific protein phosphatases domain
Domain	IPR003595	Protein-tyrosine phosphatase, catalytic
Domain	IPR020422	Dual specificity protein phosphatase domain
Family	IPR050561	Protein Tyrosine Phosphatase
Homologous_superfamily	IPR029021	Protein-tyrosine phosphatase-like

Domain Details Per Protein

Protein	Length	Dual specificity protein phosphatase domain	Protein Tyrosine Phosphatase	Protein-tyrosine phosphatase, catalytic	Protein-tyrosine phosphatase-like	Tyrosine-specific protein phosphatases domain
UniProtKB:Q6TLG9 InterPro	168
UniProtKB:Q5U3R3 InterPro	174

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	ptp4a2b-201 (1) Ensembl	Ensembl	2,222 nt	Select Tool ZFIN BLAST
mRNA	ptp4a2b-203 (1) Ensembl	Ensembl	816 nt	Select Tool ZFIN BLAST
mRNA	ptp4a2b-204 (1) Ensembl	Ensembl	5,641 nt	Select Tool ZFIN BLAST
ncRNA	ptp4a2b-003 (1) Ensembl	Ensembl	497 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations