Gene
colec11
- ID
- ZDB-GENE-041114-11
- Name
- collectin sub-family member 11
- Symbol
- colec11 Nomenclature History
- Previous Names
-
- wu:fb82e09
- zgc:103572
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to enable several functions, including calcium ion binding activity; calcium-dependent carbohydrate binding activity; and monosaccharide binding activity. Involved in developmental process. Acts upstream of or within neural crest cell migration. Predicted to be located in extracellular region. Predicted to be part of collagen trimer. Predicted to be active in extracellular space. Is expressed in head; hindbrain; liver; pronephric duct; and pronephric glomerulus. Used to study cleft palate. Human ortholog(s) of this gene implicated in 3MC syndrome 2. Orthologous to human COLEC11 (collectin subfamily member 11).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Rooryck et al., 2011
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Rooryck et al., 2011
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| 3MC syndrome 2 | Alliance | 3MC syndrome 2 | 265050 |
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| cleft palate | WT + MO1-colec11 + MO2-colec11 | standard conditions | Rooryck et al., 2011 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018378 | C-type lectin, conserved site |
| Domain | IPR001304 | C-type lectin-like |
| Domain | IPR033990 | Collectin, C-type lectin-like domain |
| Family | IPR050801 | Calcium-Dependent Lectins in Immunity and Development |
| Homologous_superfamily | IPR016186 | C-type lectin-like/link domain superfamily |
| Homologous_superfamily | IPR016187 | C-type lectin fold |
| Repeat | IPR008160 | Collagen triple helix repeat |
Domain Details Per Protein
| Protein | Length | Calcium-Dependent Lectins in Immunity and Development | Collagen triple helix repeat | Collectin, C-type lectin-like domain | C-type lectin, conserved site | C-type lectin fold | C-type lectin-like | C-type lectin-like/link domain superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q5U3G1
|
271 | |||||||
|
UniProtKB:A0A8M3AK08
|
277 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
colec11-201
(1)
|
Ensembl | 2,760 nt | ||
| mRNA |
colec11-202
(1)
|
Ensembl | 3,606 nt |
Interactions and Pathways
No data available
Plasmids
No data available