Gene
cenpf
- ID
- ZDB-GENE-041111-205
- Name
- centromere protein F
- Symbol
- cenpf Nomenclature History
- Previous Names
-
- im:7140452
- im:7144238
- im:7154719 (1)
- im:7156761
- si:ch211-152h14.2
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to have dynein complex binding activity; protein homodimerization activity; and transcription factor binding activity. Involved in animal organ development and cilium assembly. Human ortholog(s) of this gene implicated in Stromme syndrome. Is expressed in proliferative region. Orthologous to human CENPF (centromere protein F).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 16 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7144238 (1 image)
- IMAGE:7140452 (10 images)
- IMAGE:7156761 (1 image)
- IMAGE:7154719 (10 images)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Waters et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Stromme syndrome | Alliance | Stromme syndrome | 243605 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Centromere protein Cenp-F | Centromere protein Cenp-F, leucine-rich repeat-containing domain | Centromere protein Cenp-F, N-terminal | Kinetochore protein Cenp-F/LEK1, Rb protein-binding domain |
|---|---|---|---|---|---|
|
UniProtKB:F1Q7X5
|
2708 | ||||
|
UniProtKB:A0A286Y8J7
|
2675 |
Interactions and Pathways
No data available
Plasmids
No data available