Gene

mbd6

ID
ZDB-GENE-041027-3
Name
methyl-CpG binding domain protein 6
Symbol
mbd6 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have chromatin binding activity. Involved in definitive hemopoiesis and hematopoietic progenitor cell differentiation. Predicted to localize to chromocenter and nucleus. Human ortholog(s) of this gene implicated in autism spectrum disorder. Orthologous to human MBD6 (methyl-CpG binding domain protein 6).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Huang et al., 2013
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mbd6 Human Ortholog
No data available
Associated With mbd6 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001739 Methyl-CpG DNA binding
Homologous_superfamily IPR016177 DNA-binding domain superfamily
Domain Details Per Protein
Protein Length DNA-binding domain superfamily Methyl-CpG DNA binding
UniProtKB:X1WFM6 1320
UniProtKB:A0A8M3BAP7 778
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA mbd6-201 (1) Ensembl 3,867 nt
mRNA mbd6-202 (1) Ensembl 4,894 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations