Gene
mia3
- ID
- ZDB-GENE-041014-270
- Name
- MIA SH3 domain ER export factor 3
- Symbol
- mia3 Nomenclature History
- Previous Names
-
- mia2
- sb:eu1084
- si:ch211-180b22.1
- si:ch211-180b22.2
- wu:fb05c09
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport; protein secretion; and vesicle cargo loading. Predicted to localize to endoplasmic reticulum exit site and endoplasmic reticulum membrane. Is expressed in liver; median fin fold; and musculature system. Orthologous to human MIA3 (MIA SH3 domain ER export factor 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu1084 (9 images)
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Clark et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| ?Ondontochondrodysplasia 2 with hearing loss and diabetes | 619269 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | cTAGE and MIA/OTOR | SH3 domain | SH3-like domain superfamily |
|---|---|---|---|---|
|
UniProtKB:A0A8M2B7U5
|
1873 | |||
|
UniProtKB:F1R5N2
|
1874 | |||
|
UniProtKB:A0A0R4IGM8
|
1852 | |||
|
UniProtKB:Q5SP05
|
786 |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance
- Gene Tree
- Ensembl
- Note
- Woods, et al. (2005. Genome Res. 15:1307-1314.) report the 5' portion of this gene as mia2 and assigned orthology to human MIA2 based on amino acid identity. Subsequent analysis suggests their sequence is part of mia3. The mia2 gene is found on chromosome 17 with orthology to human MIA2 and mouse Mia2 based on amino acid identity and conserved synteny.