Gene

sele

ID

ZDB-GENE-041014-221

Name

selectin E

Symbol

sele Nomenclature History

Previous Names

si:ch211-260g14.8 (1)

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Description

Predicted to enable carbohydrate binding activity and metal ion binding activity. Predicted to be involved in epidermis development; lymph vessel morphogenesis; and negative regulation of complement activation, classical pathway. Predicted to act upstream of or within cell adhesion. Predicted to be located in plasma membrane. Predicted to be active in extracellular space. Is expressed in intermediate cell mass of mesoderm; posterior cardinal vein; and trunk. Human ortholog(s) of this gene implicated in IgA glomerulonephritis; brain ischemia; cerebrovascular disease; and coronary artery disease. Orthologous to human SELE (selectin E).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

4 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With sele Human Ortholog

No data available

Associated With sele Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018378	C-type lectin, conserved site
Domain	IPR000436	Sushi/SCR/CCP domain
Domain	IPR000742	EGF-like domain
Domain	IPR001304	C-type lectin-like
Domain	IPR033991	Selectin, C-type lectin-like domain
Family	IPR002396	Selectin superfamily
Family	IPR050350	Complement & Cell Adhesion Regulators
Homologous_superfamily	IPR016186	C-type lectin-like/link domain superfamily
Homologous_superfamily	IPR016187	C-type lectin fold
Homologous_superfamily	IPR035976	Sushi/SCR/CCP superfamily

Domain Details Per Protein

Protein	Length	Complement & Cell Adhesion Regulators	C-type lectin, conserved site	C-type lectin fold	C-type lectin-like	C-type lectin-like/link domain superfamily	EGF-like domain	Selectin, C-type lectin-like domain	Selectin superfamily	Sushi/SCR/CCP domain	Sushi/SCR/CCP superfamily
UniProtKB:A0A8M3AKX4 InterPro	871
UniProtKB:A0A8M3B473 InterPro	687
UniProtKB:A0A8M3ALL6 InterPro	561
UniProtKB:A0A8M6Z2N9 InterPro	561
UniProtKB:A0A8M1NL34 InterPro	872
UniProtKB:A0A8M6YUT5 InterPro	561
UniProtKB:A0A8M3AWB7 InterPro	561