Gene

trdn

ID

ZDB-GENE-041014-193

Name

triadin

Symbol

trdn Nomenclature History

Previous Names

si:dkey-72g4.2
zgc:162523

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Description

Predicted to have signaling receptor binding activity. Predicted to localize to integral component of membrane and sarcoplasmic reticulum. Human ortholog(s) of this gene implicated in catecholaminergic polymorphic ventricular tachycardia and catecholaminergic polymorphic ventricular tachycardia 5. Is expressed in adaxial cell; cardiovascular system; musculature system; and yolk syncytial layer. Orthologous to human TRDN (triadin).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

9 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6894188 (14 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from Vecchi et al., 2021
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With trdn Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
catecholaminergic polymorphic ventricular tachycardia 5	Alliance	Cardiac arrhythmia syndrome, with or without skeletal muscle weakness	615441

Associated With trdn Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR010798	Triadin

Domain Details Per Protein

Protein	Length	Triadin
UniProtKB:A3KNU6 InterPro	226
UniProtKB:Q5XJD2 InterPro	535
UniProtKB:Q32LR2 InterPro	376
UniProtKB:A0A8M6YWT4 InterPro	981
UniProtKB:A0A8M9P313 InterPro	1063
UniProtKB:A0A8M9PCB1 InterPro	1113
UniProtKB:A0A8M9PQ10 InterPro	1122
UniProtKB:A0A8M9PHX9 InterPro	1109
UniProtKB:A0A8M9PQ15 InterPro	1072
UniProtKB:A0A8M9P311 InterPro	1121
UniProtKB:A0A8M9PTE6 InterPro	1105

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	trdn-201 (1) Ensembl	Ensembl	2,641 nt	Select Tool ZFIN BLAST
mRNA	trdn-202 (1) Ensembl	Ensembl	803 nt	Select Tool ZFIN BLAST
mRNA	trdn-203 (1) Ensembl	Ensembl	1,872 nt	Select Tool ZFIN BLAST
mRNA	trdn-204 (1) Ensembl	Ensembl	771 nt	Select Tool ZFIN BLAST
ncRNA	trdn-004 (1) Ensembl	Ensembl	625 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations