Gene

ank1a

ID

ZDB-GENE-041010-44

Name

ankyrin 1, erythrocytic a

Symbol

ank1a Nomenclature History

Previous Names

ank1
si:ch211-173b16.3
wu:fa09h06
zgc:101835

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to be involved in signal transduction. Human ortholog(s) of this gene implicated in anemia; hereditary spherocytosis; and hereditary spherocytosis type 1. Orthologous to human ANK1 (ankyrin 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ank1a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
hereditary spherocytosis type 1	Alliance	Spherocytosis, type 1	182900

Associated With ank1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000488	Death domain
Domain	IPR000906	ZU5 domain
Domain	IPR040745	Ankyrin, UPA domain
Family	IPR051165	Multifunctional Ankyrin Repeat Domain-Containing Protein
Homologous_superfamily	IPR011029	Death-like domain superfamily
Homologous_superfamily	IPR036770	Ankyrin repeat-containing domain superfamily
Repeat	IPR002110	Ankyrin repeat

Domain Details Per Protein

Protein	Length	Ankyrin repeat	Ankyrin repeat-containing domain superfamily	Ankyrin, UPA domain	Death domain	Death-like domain superfamily	Multifunctional Ankyrin Repeat Domain-Containing Protein	ZU5 domain
UniProtKB:A0A0R4IN28 InterPro	1731
UniProtKB:F1QYU5 InterPro	1050
UniProtKB:B8JK17 InterPro	173
UniProtKB:A0A8M9PJY2 InterPro	2026
UniProtKB:A0A8M9PJZ5 InterPro	1985
UniProtKB:A0A8M9Q8G9 InterPro	2011
UniProtKB:A0A8M9QDT1 InterPro	2020
UniProtKB:A0A8M9PXF1 InterPro	2003
UniProtKB:A0A8M9QDU2 InterPro	1630
UniProtKB:A0A8M9Q8I4 InterPro	97
UniProtKB:A0A8M9PK01 InterPro	1619
UniProtKB:A0A8M9PXF9 InterPro	1495
UniProtKB:A0A8M9QDT5 InterPro	1997
UniProtKB:A0A8M9QDU7 InterPro	125
UniProtKB:A0A8M9PXF5 InterPro	1957
UniProtKB:A0A8M9Q357 InterPro	2022
UniProtKB:A0A8M2BCX4 InterPro	162
UniProtKB:A0A8M9PK05 InterPro	2001
UniProtKB:B8JK16 InterPro	152
UniProtKB:A0A8M9Q361 InterPro	2002
UniProtKB:A0A8M9Q363 InterPro	1843
UniProtKB:A0A8M9Q366 InterPro	173
UniProtKB:A0A8M9Q355 InterPro	2033
UniProtKB:A0A8M9Q8H4 InterPro	1989
UniProtKB:A0A8M9PJY9 InterPro	2004
UniProtKB:A0A8M9PXE5 InterPro	2026
UniProtKB:A0A0R4IFR3 InterPro	151
UniProtKB:A0A8M9QDS8 InterPro	2032
UniProtKB:A0A8M9Q8G4 InterPro	2027

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	ank1a-201 (1) Ensembl	Ensembl	3,150 nt	Select Tool ZFIN BLAST
mRNA	ank1a-203 (1) Ensembl	Ensembl	7,429 nt	Select Tool ZFIN BLAST
mRNA	ank1a-204 (1) Ensembl	Ensembl	800 nt	Select Tool ZFIN BLAST
mRNA	ank1a-205 (1) Ensembl	Ensembl	810 nt	Select Tool ZFIN BLAST
mRNA	ank1a-206 (1) Ensembl	Ensembl	1,107 nt	Select Tool ZFIN BLAST
ncRNA	si:ch211-173b16.3-002 (1) Ensembl	Ensembl	539 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations