Gene

cyp2aa8

ID
ZDB-GENE-041010-183
Name
cytochrome P450, family 2, subfamily AA, polypeptide 8
Symbol
cyp2aa8 Nomenclature History
Previous Names
  • zgc:101673
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to have heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in several processes, including exogenous drug catabolic process; organic acid metabolic process; and xenobiotic metabolic process. Predicted to localize to cytoplasm and intracellular membrane-bounded organelle.
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Hartig et al., 2016
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cyp2aa8 Human Ortholog
No data available
Associated With cyp2aa8 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017972 Cytochrome P450, conserved site
Family IPR001128 Cytochrome P450
Family IPR002401 Cytochrome P450, E-class, group I
Family IPR008069 Cytochrome P450, E-class, group I, CYP2D-like
Family IPR050182 Cytochrome P450 family 2
Homologous_superfamily IPR036396 Cytochrome P450 superfamily
Domain Details Per Protein
Protein Length Cytochrome P450 Cytochrome P450, conserved site Cytochrome P450, E-class, group I Cytochrome P450, E-class, group I, CYP2D-like Cytochrome P450 family 2 Cytochrome P450 superfamily
UniProtKB:Q5XJQ8 416
UniProtKB:A0A0R4IP03 499
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA cyp2aa8-201 (1) Ensembl 5,257 nt
mRNA cyp2aa8-202 (1) Ensembl 1,649 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations