Gene
brd1a
- ID
- ZDB-GENE-041008-168
- Name
- bromodomain containing 1a
- Symbol
- brd1a Nomenclature History
- Previous Names
-
- brd1
- im:7138929
- si:dkey-164m14.6 (1)
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to enable metal ion binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within chromatin organization. Predicted to be located in nucleus. Predicted to be part of MOZ/MORF histone acetyltransferase complex. Human ortholog(s) of this gene implicated in bipolar disorder and schizophrenia. Orthologous to human BRD1 (bromodomain containing 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7138929 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019786 | Zinc finger, PHD-type, conserved site |
| Domain | IPR000313 | PWWP domain |
| Domain | IPR001487 | Bromodomain |
| Domain | IPR001965 | Zinc finger, PHD-type |
| Domain | IPR019542 | Enhancer of polycomb-like, N-terminal |
| Domain | IPR019787 | Zinc finger, PHD-finger |
| Domain | IPR034732 | Extended PHD (ePHD) domain |
| Domain | IPR042009 | BRPF2, PHD domain |
| Family | IPR050701 | Histone Modification Regulator |
| Homologous_superfamily | IPR011011 | Zinc finger, FYVE/PHD-type |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
| Homologous_superfamily | IPR036427 | Bromodomain-like superfamily |
Domain Details Per Protein
| Protein | Length | Bromodomain | Bromodomain-like superfamily | BRPF2, PHD domain | Enhancer of polycomb-like, N-terminal | Extended PHD (ePHD) domain | Histone Modification Regulator | PWWP domain | Zinc finger, FYVE/PHD-type | Zinc finger, PHD-finger | Zinc finger, PHD-type | Zinc finger, PHD-type, conserved site | Zinc finger, RING/FYVE/PHD-type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PHX1
|
949 | ||||||||||||
|
UniProtKB:A0A8M9Q6D7
|
1141 | ||||||||||||
|
UniProtKB:F1QFR1
|
1142 |
Interactions and Pathways
No data available
Plasmids
No data available