Gene

smyd2b

ID

ZDB-GENE-041001-201

Name

SET and MYND domain containing 2b

Symbol

smyd2b Nomenclature History

Previous Names

si:dkey-121j17.3 (1)
zgc:136609

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Description

Predicted to have RNA polymerase II complex binding activity and histone methyltransferase activity (H3-K36 specific). Involved in heart contraction and heart development. Predicted to localize to cytosol and nucleus. Is expressed in muscle cell and somite. Orthologous to human SMYD2 (SET and MYND domain containing 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

4 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With smyd2b Human Ortholog

No data available

Associated With smyd2b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001214	SET domain
Domain	IPR002893	Zinc finger, MYND-type
Domain	IPR044419	SMYD2, SET domain
Family	IPR050869	Histone-lysine N-methyltransferase
Homologous_superfamily	IPR011990	Tetratricopeptide-like helical domain superfamily
Homologous_superfamily	IPR046341	SET domain superfamily

Domain Details Per Protein

Protein	Length	Histone-lysine N-methyltransferase	SET domain	SET domain superfamily	SMYD2, SET domain	Tetratricopeptide-like helical domain superfamily	Zinc finger, MYND-type
UniProtKB:T1ECS2 InterPro	437
UniProtKB:Q5RGL7 InterPro	434

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	smyd2b-201 (1) Ensembl	Ensembl	1,553 nt	Select Tool ZFIN BLAST
mRNA	smyd2b-202 (1) Ensembl	Ensembl	2,812 nt	Select Tool ZFIN BLAST
mRNA	smyd2b-203 (1) Ensembl	Ensembl	760 nt	Select Tool ZFIN BLAST
mRNA	smyd2b-204 (1) Ensembl	Ensembl	5,568 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations