Gene
gtf2h5
- ID
- ZDB-GENE-041001-144
- Name
- general transcription factor IIH, polypeptide 5
- Symbol
- gtf2h5 Nomenclature History
- Previous Names
-
- ttda (1)
- si:dkey-12h9.4
- zgc:153434
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to be involved in nucleotide-excision repair, preincision complex assembly; phosphorylation of RNA polymerase II C-terminal domain; and transcription by RNA polymerase II. Predicted to act upstream of or within nucleotide-excision repair and transcription initiation at RNA polymerase II promoter. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIIH core complex and transcription factor TFIIH holo complex. Human ortholog(s) of this gene implicated in photosensitive trichothiodystrophy 3. Orthologous to human GTF2H5 (general transcription factor IIH subunit 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| photosensitive trichothiodystrophy 3 | Alliance | Trichothiodystrophy 3, photosensitive | 616395 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | TFB5-like superfamily | TFIIH subunit TTDA/Tfb5 |
|---|---|---|---|
|
UniProtKB:Q5SNQ6
|
71 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
gtf2h5-201
(1)
|
Ensembl | 714 nt | ||
| mRNA |
gtf2h5-202
(1)
|
Ensembl | 686 nt | ||
| mRNA |
gtf2h5-203
(1)
|
Ensembl | 911 nt | ||
| mRNA |
gtf2h5-204
(1)
|
Ensembl | 822 nt | ||
| mRNA |
gtf2h5-205
(1)
|
Ensembl | 764 nt |
Interactions and Pathways
No data available
Plasmids
No data available