Gene

bach2b

ID
ZDB-GENE-041001-139
Name
BTB and CNC homology 1, basic leucine zipper transcription factor 2b
Symbol
bach2b Nomenclature History
Previous Names
  • bach2
  • si:dkeyp-4f12.1
  • si:dkeyp-4f12.2
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to have DNA binding activity and DNA-binding transcription factor activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Is expressed in head and trunk. Orthologous to human BACH2 (BTB domain and CNC homolog 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With bach2b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
immunodeficiency 60 Alliance Immunodeficiency 60 and autoimmunity 618394
Associated With bach2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000210 BTB/POZ domain
Domain IPR004826 Basic leucine zipper domain, Maf-type
Domain IPR004827 Basic-leucine zipper domain
Domain IPR043321 BACH, basic leucine zipper (bZIP) domain
Family IPR050457 Zinc finger and BTB domain-containing
Homologous_superfamily IPR008917 Transcription factor, Skn-1-like, DNA-binding domain superfamily
Homologous_superfamily IPR011333 SKP1/BTB/POZ domain superfamily
Homologous_superfamily IPR046347 Basic-leucine zipper domain superfamily
Domain Details Per Protein
Protein Length BACH, basic leucine zipper (bZIP) domain Basic-leucine zipper domain Basic leucine zipper domain, Maf-type Basic-leucine zipper domain superfamily BTB/POZ domain SKP1/BTB/POZ domain superfamily Transcription factor, Skn-1-like, DNA-binding domain superfamily Zinc finger and BTB domain-containing
UniProtKB:Q5RIW6 823
UniProtKB:A0A8N7UQL1 797
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA bach2b-201 (1) Ensembl 4,693 nt
mRNA bach2b-204 (1) Ensembl 2,322 nt
ncRNA bach2b-002 (1) Ensembl 543 nt
ncRNA bach2b-003 (1) Ensembl 540 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations