Gene
cfap298
- ID
- ZDB-GENE-040930-8
- Name
- cilia and flagella associated protein 298
- Symbol
- cfap298 Nomenclature History
- Previous Names
-
- cfap298
- c10h21orf59
- c21orf59
- c21orf59l
- grb
- Kurly (1)
- sb:cb615
- unm tj271
- unm tm304
- unm_tj271
- zgc:64057
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Involved in several processes, including cerebrospinal fluid circulation; motile cilium assembly; and pronephros morphogenesis. Predicted to localize to cilium; cytoplasm; and cytoskeleton. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 26. Is expressed in several structures, including Kupffer's vesicle; axis; mesoderm; pronephros; and sensory system. Orthologous to human CFAP298 (cilia and flagella associated protein 298).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb615 (14 images)
Wild Type Expression Summary
- All Phenotype Data
- 28 figures from 14 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| primary ciliary dyskinesia 26 | Alliance | Ciliary dyskinesia, primary, 26 | 615500 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR021298 | Cilia- and flagella-associated protein 298 |
Domain Details Per Protein
| Protein | Length | Cilia- and flagella-associated protein 298 |
|---|---|---|
|
UniProtKB:B7ZVU8
|
290 | |
|
UniProtKB:Q6DRC3
|
290 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cfap298-201
(1)
|
Ensembl | 1,520 nt | ||
| mRNA |
cfap298-202
(1)
|
Ensembl | 1,748 nt |
Interactions and Pathways
No data available
Plasmids
No data available