Gene

ppp2r1bb

ID

ZDB-GENE-040927-20

Name

protein phosphatase 2, regulatory subunit A, beta b

Symbol

ppp2r1bb Nomenclature History

Previous Names

ppp2r1b
ik:tdsubc_2h3
tdsubc_2h3
wu:fa11a11
wu:fb38a08
xx:tdsubc_2h3
zgc:92493

Type

protein_coding_gene

Location

Chr: 15 Mapping Details/Browsers

Description

Predicted to enable protein phosphatase regulator activity. Predicted to be involved in protein dephosphorylation. Predicted to be part of protein phosphatase type 2A complex. Predicted to be active in cytoplasm. Is expressed in female organism. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 36. Orthologous to several human genes including PPP2R1B (protein phosphatase 2 scaffold subunit Abeta).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:92493 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ppp2r1bb Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
lung cancer	Alliance	Lung cancer, somatic	211980

Associated With ppp2r1bb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR054573	Phosphatase PP2A regulatory subunit A/Splicing factor 3B subunit 1-like, HEAT repeat
Family	IPR051023	Protein Phosphatase 2A Regulatory Subunit A
Homologous_superfamily	IPR011989	Armadillo-like helical
Homologous_superfamily	IPR016024	Armadillo-type fold
Repeat	IPR000357	HEAT repeat
Repeat	IPR021133	HEAT, type 2