Gene
cldn2
- ID
- ZDB-GENE-040912-26
- Name
- claudin 2
- Symbol
- cldn2 Nomenclature History
- Previous Names
-
- zgc:92260
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable structural molecule activity. Predicted to be involved in bicellular tight junction assembly and cell adhesion. Predicted to be located in cell junction and membrane. Predicted to be active in bicellular tight junction and plasma membrane. Is expressed in brain; eye; gonad; immune system; and liver. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 29. Orthologous to human CLDN14 (claudin 14) and CLDN2 (claudin 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:92260 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| ?Azoospermia, obstructive, with nephrolithiasis | 301060 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Claudin | Claudin, conserved site | PMP-22/EMP/MP20/Claudin |
|---|---|---|---|---|
|
UniProtKB:A0A8M2BHN3
|
270 |
Interactions and Pathways
No data available
Plasmids
No data available