Gene

cratb

ID
ZDB-GENE-040912-162
Name
carnitine O-acetyltransferase b
Symbol
cratb Nomenclature History
Previous Names
  • crat
  • wu:fc39c02
  • zgc:92131
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to have carnitine O-acetyltransferase activity. Predicted to be involved in carnitine metabolic process, CoA-linked. Predicted to localize to peroxisome. Human ortholog(s) of this gene implicated in neurodegeneration with brain iron accumulation. Orthologous to human CRAT (carnitine O-acetyltransferase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cratb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
?Neurodegeneration with brain iron accumulation 8 617917
Associated With cratb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR039551 Choline/carnitine acyltransferase domain
Family IPR000542 Acyltransferase ChoActase/COT/CPT
Homologous_superfamily IPR023213 Chloramphenicol acetyltransferase-like domain superfamily
Homologous_superfamily IPR042231 Choline/Carnitine o-acyltransferase, domain 2
Domain Details Per Protein
Protein Length Acyltransferase ChoActase/COT/CPT Chloramphenicol acetyltransferase-like domain superfamily Choline/carnitine acyltransferase domain Choline/Carnitine o-acyltransferase, domain 2
UniProtKB:A3KPZ2 614
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA cratb-201 (1) Ensembl 2,523 nt
mRNA cratb-202 (1) Ensembl 2,592 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations