Gene

lypd6

ID

ZDB-GENE-040912-117

Name

LY6/PLAUR domain containing 6

Symbol

lypd6 Nomenclature History

Previous Names

zgc:101899 (1)

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Description

Predicted to have acetylcholine receptor inhibitor activity. Involved in Spemann organizer formation and regulation of Wnt signaling pathway. Localizes to anchored component of plasma membrane. Is expressed in several structures, including DEL; hypoblast; margin; nervous system; and optic vesicle. Orthologous to human LYPD6 (LY6/PLAUR domain containing 6).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

IMAGE:6897270 (10 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Özhan et al., 2013
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With lypd6 Human Ortholog

No data available

Associated With lypd6 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR039457	Ly6/PLAUR domain-containing protein 6-like
Homologous_superfamily	IPR045860	Snake toxin-like superfamily

Domain Details Per Protein

Protein	Length	Ly6/PLAUR domain-containing protein 6-like	Snake toxin-like superfamily
UniProtKB:A0A8M9Q4J3 InterPro	174
UniProtKB:Q66IA6 InterPro	174

Transcripts

Genome Browsers

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	lypd6-201 (1) Ensembl	Ensembl		1,237 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations