Gene
ect2
- ID
- ZDB-GENE-040831-2
- Name
- epithelial cell transforming 2
- Symbol
- ect2 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to have GTPase activator activity and guanyl-nucleotide exchange factor activity. Involved in cytokinetic process. Predicted to localize to cytoplasm and nucleus. Is expressed in midbrain. Orthologous to human ECT2 (epithelial cell transforming 2).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR001331 | Guanine-nucleotide dissociation stimulator, CDC24, conserved site |
Domain | IPR000219 | Dbl homology (DH) domain |
Domain | IPR001357 | BRCT domain |
Domain | IPR049395 | ECT2, PH domain |
Domain | IPR049396 | ECT2, BRCT0 domain |
Family | IPR026817 | Guanine nucleotide exchange factor Ect2 |
Homologous_superfamily | IPR011993 | PH-like domain superfamily |
Homologous_superfamily | IPR035899 | Dbl homology (DH) domain superfamily |
Homologous_superfamily | IPR036420 | BRCT domain superfamily |
Domain Details Per Protein
Protein | Length | BRCT domain | BRCT domain superfamily | Dbl homology (DH) domain | Dbl homology (DH) domain superfamily | ECT2, BRCT0 domain | ECT2, PH domain | Guanine-nucleotide dissociation stimulator, CDC24, conserved site | Guanine nucleotide exchange factor Ect2 | PH-like domain superfamily |
---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:A0A8M2B1T9
|
946 | |||||||||
UniProtKB:Q6DRB9
|
878 | |||||||||
UniProtKB:F1QVS6
|
976 | |||||||||
UniProtKB:A0A2R8Q1Z1
|
980 | |||||||||
UniProtKB:A0A8M2B2N3
|
1012 |
Interactions and Pathways
No data available
Plasmids
No data available