Gene

ect2

ID
ZDB-GENE-040831-2
Name
epithelial cell transforming 2
Symbol
ect2 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have GTPase activator activity and guanyl-nucleotide exchange factor activity. Involved in cytokinetic process. Predicted to localize to cytoplasm and nucleus. Is expressed in midbrain. Orthologous to human ECT2 (epithelial cell transforming 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ect2 Human Ortholog
No data available
Associated With ect2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR001331 Guanine-nucleotide dissociation stimulator, CDC24, conserved site
Domain IPR000219 Dbl homology (DH) domain
Domain IPR001357 BRCT domain
Domain IPR049395 ECT2, PH domain
Domain IPR049396 ECT2, BRCT0 domain
Family IPR026817 Guanine nucleotide exchange factor Ect2
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR035899 Dbl homology (DH) domain superfamily
Homologous_superfamily IPR036420 BRCT domain superfamily
Domain Details Per Protein
Protein Length BRCT domain BRCT domain superfamily Dbl homology (DH) domain Dbl homology (DH) domain superfamily ECT2, BRCT0 domain ECT2, PH domain Guanine-nucleotide dissociation stimulator, CDC24, conserved site Guanine nucleotide exchange factor Ect2 PH-like domain superfamily
UniProtKB:A0A8M2B1T9 946
UniProtKB:Q6DRB9 878
UniProtKB:F1QVS6 976
UniProtKB:A0A2R8Q1Z1 980
UniProtKB:A0A8M2B2N3 1012
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA ect2-201 (1) Ensembl 3,054 nt
mRNA ect2-202 (1) Ensembl 4,186 nt
mRNA ect2-203 (1) Ensembl 4,793 nt
mRNA ect2-204 (1) Ensembl 8,427 nt
mRNA ect2-205 (1) Ensembl 8,263 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations