Gene

snrnp70

ID

ZDB-GENE-040825-2

Name

small nuclear ribonucleoprotein 70 (U1)

Symbol

snrnp70 Nomenclature History

Previous Names

snrp70
U1 small ribonucleoprotein 70kd (1)
wu:fc20b04
zgc:136450

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Predicted to enable U1 snRNA binding activity and mRNA binding activity. Acts upstream of or within hematopoietic stem cell differentiation. Predicted to be located in nucleus. Predicted to be part of U1 snRNP and U2-type prespliceosome. Is expressed in central nervous system; hematopoietic stem cell; and motor neurons. Human ortholog(s) of this gene implicated in disease of mental health and systemic lupus erythematosus. Orthologous to human SNRNP70 (small nuclear ribonucleoprotein U1 subunit 70).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7147833 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 5 figures from 4 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With snrnp70 Human Ortholog

No data available

Associated With snrnp70 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000504	RNA recognition motif domain
Domain	IPR022023	U1 small nuclear ribonucleoprotein of 70kDa N-terminal
Domain	IPR034143	snRNP70, RNA recognition motif
Family	IPR051183	U1 snRNP 70 kDa and U11/U12 snRNP 35 kDa
Homologous_superfamily	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily	IPR035979	RNA-binding domain superfamily