Gene
rabl3
- ID
- ZDB-GENE-040808-11
- Name
- RAB, member of RAS oncogene family-like 3
- Symbol
- rabl3 Nomenclature History
- Previous Names
-
- fb40b02
- wu:fb40b02
- zgc:100876 (1)
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to enable GTP binding activity; GTPase activity; and protein homodimerization activity. Predicted to be involved in several processes, including lymphocyte differentiation; regulation of Ras protein signal transduction; and regulation of protein lipidation. Predicted to act upstream of or within proteolysis. Predicted to be active in endomembrane system. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human RABL3 (RAB, member of RAS oncogene family like 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7141370 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Nissim et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {?Pancreatic cancer, susceptibility to, 5} | 618680 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
| Protein | Length | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|
|
UniProtKB:Q6TNS7
|
233 |
Interactions and Pathways
No data available
Plasmids
No data available