Gene
ndufa7
- ID
- ZDB-GENE-040801-169
- Name
- NADH:ubiquinone oxidoreductase subunit A7
- Symbol
- ndufa7 Nomenclature History
- Previous Names
-
- zgc:92850
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Acts upstream of or within heart development and regulation of calcineurin-mediated signaling. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex I. Is expressed in several structures, including alar plate midbrain region; eye; immature eye; midbrain; and pectoral fin musculature. Used to study hypertrophic cardiomyopathy. Orthologous to human NDUFA7 (NADH:ubiquinone oxidoreductase subunit A7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:92850 (15 images)
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Shi et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| hypertrophic cardiomyopathy | twu34Tg + MO1-ndufa7 | standard conditions | Shi et al., 2020 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR009947 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 |
Domain Details Per Protein
| Protein | Length | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 |
|---|---|---|
|
UniProtKB:Q6DGM9
|
104 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ndufa7-201
(1)
|
Ensembl | 482 nt |
Interactions and Pathways
No data available
Plasmids
No data available