Gene
rpl18
- ID
- ZDB-GENE-040801-165
- Name
- ribosomal protein L18
- Symbol
- rpl18 Nomenclature History
- Previous Names
-
- fa98d03
- wu:fa98d03
- zgc:92872 (1)
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Acts upstream of or within erythrocyte maturation. Predicted to be located in ribosome and rough endoplasmic reticulum. Predicted to be part of cytosolic large ribosomal subunit. Is expressed in eye; head; intestine; liver; and pectoral fin bud. Used to study Diamond-Blackfan anemia. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 18. Orthologous to human RPL18 (ribosomal protein L18).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6895524 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 7 figures from Chen et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Diamond-Blackfan anemia 18 | Alliance | ?Diamond-Blackfan anemia 18 | 618310 |
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| Diamond-Blackfan anemia | rpl18zf3219/zf3219 (TU) | standard conditions | Chen et al., 2020 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Large ribosomal subunit protein eL18 | Large ribosomal subunit protein eL18, conserved site | Large ribosomal subunit protein uL15/eL18 | Large ribosomal subunit protein uL15/eL18 superfamily |
|---|---|---|---|---|---|
|
UniProtKB:Q6DGL0
|
182 |
Interactions and Pathways
No data available
Plasmids
No data available