Gene

ticrr

ID

ZDB-GENE-040728-1

Name

TopBP1-interacting, checkpoint, and replication regulator

Symbol

ticrr Nomenclature History

Previous Names

5730590G19-like (1)
mgc45866l

Type

protein_coding_gene

Location

Chr: 25 Mapping Details/Browsers

Description

Predicted to have chromatin binding activity. Involved in several processes, including DNA repair; mitotic G2/M transition checkpoint; and response to ionizing radiation. Predicted to localize to nucleus. Orthologous to human TICRR (TOPBP1 interacting checkpoint and replication regulator).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Zhao et al., 2017

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 6 figures from 3 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ticrr Human Ortholog

No data available

Associated With ticrr Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR032746	Treslin, M domain
Domain	IPR053919	Treslin, N-terminal domain
Domain	IPR053920	Treslin, STD domain
Family	IPR026153	Treslin

Domain Details Per Protein

Protein	Length	Treslin	Treslin, M domain	Treslin, N-terminal domain	Treslin, STD domain
UniProtKB:Q6DRL4 InterPro	1824

Transcripts

Genome Browsers

NCBI

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
pseudogenic transcript	ticrr-001 (1) Ensembl	Ensembl		5,907 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations