Gene

dnm3a

ID

ZDB-GENE-040724-76

Name

dynamin 3a

Symbol

dnm3a Nomenclature History

Previous Names

dnm3
si:dkey-19f21.3

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Description

Predicted to enable GTPase activity and microtubule binding activity. Predicted to be involved in receptor internalization and synaptic vesicle budding from presynaptic endocytic zone membrane. Predicted to act upstream of or within endocytosis. Predicted to be active in several cellular components, including microtubule; plasma membrane; and synapse. Is expressed in heart; liver; muscle; nervous system; and neural tube. Orthologous to human DNM3 (dynamin 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With dnm3a Human Ortholog

No data available

Associated With dnm3a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR019762	Dynamin, GTPase region, conserved site
Domain	IPR000375	Dynamin stalk domain
Domain	IPR001401	Dynamin, GTPase domain
Domain	IPR001849	Pleckstrin homology domain
Domain	IPR003130	Dynamin GTPase effector
Domain	IPR020850	GTPase effector domain
Domain	IPR030381	Dynamin-type guanine nucleotide-binding (G) domain
Domain	IPR045063	Dynamin, N-terminal
Family	IPR022812	Dynamin
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase

Domain Details Per Protein

Protein	Length	Dynamin	Dynamin, GTPase domain	Dynamin GTPase effector	Dynamin, GTPase region, conserved site	Dynamin, N-terminal	Dynamin stalk domain	Dynamin-type guanine nucleotide-binding (G) domain	GTPase effector domain	PH-like domain superfamily	Pleckstrin homology domain	P-loop containing nucleoside triphosphate hydrolase
UniProtKB:A0A8M3AKP9 InterPro	835
UniProtKB:A0A8M6YU68 InterPro	537
UniProtKB:Q5RHR9 InterPro	825

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	dnm3a-201 (1) Ensembl	Ensembl	4,016 nt	Select Tool ZFIN BLAST
mRNA	dnm3a-202 (1) Ensembl	Ensembl	860 nt	Select Tool ZFIN BLAST
mRNA	dnm3a-203 (1) Ensembl	Ensembl	2,966 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations